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Genomics, Precision Medicine, and Big Data in Oncology

Cancer Treatment Centers of America

Dr. Brion Randolph of Cancer Treatment Centers of America talks genomics, precision medicine, and big data in oncology

Genomics, Precision Medicine, and Big Data in Oncology

We sat down with medical oncologist/hematologist, Dr. Brion Randolph, of Cancer Treatment Centers of America stopped by to talk about the impacts of genomics, precision medicine, and big data in oncology.  Dr. Randolph serves as the Chief Hematologist for the Cancer Treatment Centers facility located in Newnan, GA.

Randolph explained how genomics, or the study of DNA material of cancer cells to identify mutations that serve as “drivers” for their tumor cells.  The information gained is used to find the genetic information that turns these cancer cells on and off.  In some cases this data can reveal factors about the tumor cells that can be used when deciding what medication the physician should prescribe.  Often, this genetic data can indicate that another medicine that was originally used to treat another form of cancer in another region of the body could be effective for this particular patient’s case.

We also discussed how oncology is advancing in its use of big data, enabling multiple centers and research studies to leverage results from around the community to advance their work and/or discover trends or commonalities.  Dr. Randolph also explained how we still have a distance to go before we have a broad acceptance and participation in big data as organizations seek to protect and leverage their discoveries and results.

Special Guest:

Dr. Brion Randolph, Chief Medical Hematologist, Cancer Treatment Centers of America, GA  twitter_logo_small  facebook_logo_small3  Pinterest LOGO  google-plus-logo-red-265px  youtube-logo1

Dr. Brion Randolph

  • MS, Nuclear Engineering, University of Tennessee
  • Doctor of Medicine, University of South Carolina College of Medicine
  • Residency, Baylor University College of Medicine
  • Fellowship, Baylor University College of Medicine
  • Board Certified, Internal Medicine and Hematology and Oncology

 

 

Intent Solutions and NFANT Labs

healthcare technology

Lou Malice, Sam Zamarippa, Jay Shaffer, Tommy Cunningham

Intent Solutions and NFANT Labs

We sat down with experts from two Atlanta area health technology companies, Intent Solutions and NFANT Labs.  Joining us in studio were Lou Malice, Sam Zamarippa, and Tommy Cunningham.  Intent Solutions is a start-up that is developing a device aimed at improving compliance with prescribed medication regimens, as well as helping to improve likelihood the intended person has access to the medicine.

In its early phase of development, Intent Solutions has positioned itself to be an effective tool for pharmaceutical research studies.  In these studies, it is vital that participants adhere to the prescribed medication regimen in order to obtain the most effective and accurate test results.

The Intent Solutions device has a secure chamber that contains the pills for the particular prescription.  Called “TAD” (standing for “take as directed”), the device utilizes fingerprint technology to identify the user before dispensing medication.  Additionally, the TAD device is able to connect with the patient’s mobile device (and the prescribing entity) to share updates on efforts to access medication by unauthorized users, whether medication was dispensed, and it can send the patient reminders, prompting them to take their medication.

In this way, the TAD device facilitates medication research by improving compliance with the schedule the medication was intended to be taken on.

NFANT Labs has developed a device that uses sensors that can give a care giver visual feedback on a monitor regarding a NICU baby’s sucking patterns while feeding, a task that for many premies is challenging.  Until now, the only way a practitioner could assess the sucking strength and patterns was to literally use a finger in the infant’s mouth.

The difficulty these young babies face is often related to a weak tongue, ineffective tongue movements, and uncoordinated swallowing timing.  This predisposes them to consuming inadequate calories as well as creating the risk for aspiration pneumonia, both of which can lead to additional length of stay and even mortality.

The NFANT Labs monitor fits between the nipple and the bottle used to feed the child.  It has a sensor that detects the up and down motion of the tongue, as well as negative pressure being generated by the suckling infant.  It converts the data to wave forms on a monitor that the care giver can follow, allowing them to slow or pause feeding to allow the child to “catch up” with dispensed milk or to re-position them them to assess whether it leads to a more effective sucking pattern.

Special Guests:

Lou Malice, CEO of Intent Solutions and NFANT Labs

Intent Solutions

Sam Zamarippa, VP of Strategy and Business Development, Intent Solutions

Intent Solutions

Tommy Cunningham, Co-founder of NFANT Labs

NFANT Labs

Georgia Dental Association

Oral Health

Becky Weinman, Evis Babo, and Tom Broderick talk oral health

Georgia Dental Association

On this week’s episode we featured president of the Georgia Dental Association and practicing Savannah orthodontist, Tom Broderick, along with members, Evis Babo and Becky Weinman, both Atlanta-based general dentists.

We discussed the mission of the Georgia Dental Association, along with various initiatives the association is working on to foster oral health for Georgians such as the Mission of Mercy.  With this program, members of the association from around the state join forces to contribute their time and resources to provide free dental care to citizens who are economically-challenged but that are in need of dental care.

As our guests described, in many cases these patients are able to get smiles restored with dentures or other procedures that allow them to more successfully apply for jobs they might not have been able to before.  We also talked about how the association members are engaging providers in elderly residential and care facilities to teach them how to better meet basic preventive care needs.

The panel explained the importance of each of us establishing a “dental home” where we go for regular preventive care and assessment (ideally 2x per year).  The reason for this, as Becky described, is that cavities and some other problems can develop and progress a great deal in a year’s time.  By identifying and treating developing problems quickly, the treatment needed to correct these issues is typically very easy and comparatively inexpensive compared to advanced measures such as crowns or extractions.

Weinman, Babo, and Broderick also shared information about the fact that dentists utilize these regular visits to assess the patient for problems such as oral cancer, diabetes, and other health problems that have signs that can be seen in the mouth.  In this way, the patient gains another provider who can help catch serious developing health problems and seek treatment while there is an opportunity to reverse them or treat them more easily.

Special Guests:

Tom Broderick, DDS, President of Georgia Dental Association  twitter_logo_small

Georgia Dental Association

Evis Babo, DMD, of Peachtree Smile Center  twitter_logo_small  facebook_logo_small3  google-plus-logo-red-265px

Peachtree Smile Center

Becky Weinman, DDS, of Buckhead Dental Associates   facebook_logo_small3

Buckhead Dental Associates

Telehealth

MyIdealDoctor

Adrian Davis of MyIdealDoctor talks telehealth

Telehealth

This week we sat down with Adrian Davis, CEO of MyIdealDoctor, a telehealth company.  Adrian shared how he had spent the early years of his career in health technology and equipment sales and distribution.  With the passage of the ACA he and several of his associates saw an opportunity to help meet a need for access to medical care, taking advantage of technology.

They launched the company to begin to help patients to be able to speak directly with a physician from wherever they are using phone, smart phone/mobile device, or via a computer connection.  Their initial focus has been upon episodic patient needs centered around non-emergent complaints such as respiratory infections, minor cuts, sore throats, etc.

In many cases the physician is able to use the camera on the device, along with interview, to make a diagnosis and prescribe medication to treat the problem.  Additionally, if the patient’s complaint is too severe or worrisome to be able to handle the problem remotely, they make recommendations to seek care in a nearby urgent care center or emergency department.

In this way MyIdealDoctor is able to have an impact on the volume of patients being seen in the urgent care and more importantly, in the emergency rooms, allowing them to focus on more acutely-ill patients.

The company has focused their initial service model on corporate health, providing their care model to businesses offering the service as a component of their employee health plans.  MyIdealDoctor will be providing their service to the general population soon.

Special Guest:

Adrian Davis, CEO/ Co-founder of MyIdealDoctor  twitter_logo_small  linkedin_small1  facebook_logo_small3

MyIdealDoctor

  • BS, Microbiology, University of Georgia
  • Co-founder/Partner, United Medical Enterprises
  • Previous GI/Ultrasound Territory Manager, Philips
  • Former IV Therapy Territory Manager, Baxter Healthcare